Head-to-head · WeighScore
Onyx Weight Loss vs Prime Health
The verdict
Prime Health takes it — 59.4/100 to 58.8/100, but only just.
Prime Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Prime Health (joinprimehealth.com) is a LegitScript-certified GLP-1 telehealth platform offering compounded semaglutide and tirzepatide for weight loss. Onyx Weight Loss is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Onyx Weight Loss | Prime Health |
|---|---|---|
| WeighScore | 58.8/100 | 59.4/100 |
| Grade | C | C |
| Scorecard rank | #358 | #344 |
| Semaglutide | $228/mo (starting dose, compounded) | $299/mo (compounded) |
| Tirzepatide | $280/mo (starting dose, compounded) | $399/mo (compounded) |
| Coverage | 8 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #358 · C
Strengths
- Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
- Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
- Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
- Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
- Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team
Where it loses points
- Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
- No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
- Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
- Labs not included or mentioned; no baseline bloodwork protocol published
- Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
Graded #344 · C
Strengths
- LegitScript-certified platform
- Flat pricing that does not rise as dosage increases
- Bundle includes medication, labs, shipping, and unlimited clinician access
- Money-back guarantee of at least 10% body-weight loss in 4 months
- Fast 24-hour prescription review and 5-7 day delivery
Where it loses points
- Compounded medications only; no FDA-approved brand options listed
- Not available in Louisiana
- Care delivered through third-party clinician groups, not in-house
- Named compounding pharmacy not disclosed
- No insurance accepted
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.