Head-to-head · WeighScore
Onyx Weight Loss vs Peptivo
The verdict
Peptivo takes it — 60.1/100 to 58.8/100, but only just.
Peptivo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Peptivo is a 100% online GLP-1 weight-loss telehealth service offering compounded medication made in the USA at FDA-registered labs, with same-day provider visits and 24/7 messaging. Onyx Weight Loss is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Onyx Weight Loss | Peptivo |
|---|---|---|
| WeighScore | 58.8/100 | 60.1/100 |
| Grade | C | C |
| Scorecard rank | #358 | #331 |
| Semaglutide | $228/mo (starting dose, compounded) | Not disclosed |
| Tirzepatide | $280/mo (starting dose, compounded) | Not disclosed |
| Coverage | 8 states | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #358 · C
Strengths
- Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
- Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
- Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
- Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
- Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team
Where it loses points
- Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
- No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
- Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
- Labs not included or mentioned; no baseline bloodwork protocol published
- Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
Graded #331 · C
Strengths
- Low entry pricing — GLP-1 weight-loss plans starting at $169/mo, with free discreet shipping
- Same-day provider visits and 24/7 provider messaging; 100% online
- Compounded in the USA at FDA-registered labs; can also prescribe brand GLP-1 (Ozempic, Wegovy, Zepbound)
- FSA/HSA eligible with upfront pricing
Where it loses points
- GLP-1 products use generic names ('GLP-1 Daily Support', 'Weight Loss Boost') — semaglutide/tirzepatide not clearly broken out
- Compounding pharmacy/lab partner not named
- Limited published policies (privacy and terms only; no HIPAA notice or refund policy found)
- Not LegitScript-certified (no certification displayed)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.