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Head-to-head · WeighScore

Onyx Weight Loss vs Optimized Health

Onyx Weight Loss
Graded #359

Lower grade

vs+8.400000000000006
Optimized Health
Graded #166

Higher grade

The verdict

Optimized Health takes it — 67.2/100 to 58.8/100.

Optimized Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Optimized Health is a concierge medical weight loss and hormone clinic offering clinician-supervised GLP-1 programs with compounded semaglutide and tirzepatide, plus oral options like phentermine.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueOptimized Health +2
43
45
Dose & formulationOptimized Health +11
64
75
Clinical oversightOptimized Health +1
75
76
Labs & monitoringOptimized Health +26
63
89
FulfillmentOptimized Health +14
53
67
Contract termsEven
55
55
Onyx Weight Loss · left barOptimized Health · right bar

The numbers

MetricOnyx Weight LossOptimized Health
WeighScore58.8/10067.2/100
GradeCC
Scorecard rank#359#166
Semaglutide$228/mo (starting dose, compounded)$200/mo (starting dose, compounded)
Tirzepatide$280/mo (starting dose, compounded)$250/mo (starting dose, compounded)
Coverage8 states5 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
Optimized Health

Graded #166 · C

Strengths

  • Fully transparent pricing published on the website
  • Semaglutide from $200/mo and tirzepatide from $250/mo
  • Lab panels included with clinician-supervised dosing
  • LegitScript certified clinic
  • Lead PA-C with over a decade in obesity medicine

Where it loses points

  • Telehealth limited to MO, IA, KS, UT, and WA
  • Compounded GLP-1 only, not brand-name
  • No insurance billing (cash-pay)
  • PA-led rather than MD/DO-led

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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