Head-to-head · WeighScore
Onyx Weight Loss vs Open Water Rx
The verdict
Too close to call — both grade 58.8/100 (C).
Onyx Weight Loss and Open Water Rx land on the same WeighScore, so neither clears the other on our six graded dimensions. Onyx Weight Loss sits one line higher on the board (#359 vs #360) on the underlying tiebreak, but it's a genuine coin-flip — pick on the factors and prices that matter most to you below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Onyx Weight Loss | Open Water Rx |
|---|---|---|
| WeighScore | 58.8/100 | 58.8/100 |
| Grade | C | C |
| Scorecard rank | #359 | #360 |
| Semaglutide | $228/mo (starting dose, compounded) | $249/mo (compounded) |
| Tirzepatide | $280/mo (starting dose, compounded) | $339/mo (compounded) |
| Coverage | 8 states | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #359 · C
Strengths
- Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
- Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
- Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
- Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
- Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team
Where it loses points
- Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
- No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
- Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
- Labs not included or mentioned; no baseline bloodwork protocol published
- Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
Graded #360 · C
Strengths
- Combines weight-loss and longevity verticals in one brand
- Established brand domain
Where it loses points
- Limited public data — most details are gated behind signup or rendered only in JavaScript
- Pricing not disclosed
- GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
- States-served list not disclosed
- Pharmacy partner not named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.