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Head-to-head · WeighScore

Nucore Health vs Vaylen

Nucore Health
Graded #367

Lower grade

vs+19.300000000000004
Vaylen
Graded #44

Higher grade

The verdict

Vaylen takes it — 77.9/100 to 58.6/100.

Vaylen grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Vaylen is a pure GLP-1 specialist offering compounded semaglutide ($179/mo), compounded tirzepatide ($239/mo), compounded oral GLP-1 ($259/mo), and brand-name Ozempic, Zepbound, and Wegovy.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueVaylen +31
36
67
Dose & formulationVaylen +24
64
88
Clinical oversightVaylen +2
82
84
Labs & monitoringVaylen +24
53
77
FulfillmentVaylen +23
67
90
Contract termsEven
55
55
Nucore Health · left barVaylen · right bar

The numbers

MetricNucore HealthVaylen
WeighScore58.6/10077.9/100
GradeCC+
Scorecard rank#367#44
Semaglutide$299/mo (starting dose, compounded)$179/mo (compounded)
Tirzepatide$199/mo (microdose tier, compounded)$239/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
Nucore Health

Graded #367 · C

Strengths

  • Physician-owned and LegitScript Certified — strong trust signals
  • Available nationwide in all 50 states
  • Care and pharmacy fulfillment run on OpenLoop Health's licensed network
  • Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12

Where it loses points

  • Published pricing is gated behind the intake quiz — no upfront cost shown
  • Legal terms and privacy are posted as downloadable documents, not web pages
  • Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
  • Longevity and microdose positioning is marketing; evidence varies by use
Vaylen

Graded #44 · C+

Strengths

  • Pure GLP-1 specialist — not a multi-category telehealth platform
  • All 50 states coverage with licensed clinicians
  • Both compounded and brand-name options (Ozempic, Wegovy, Zepbound)
  • Oral GLP-1 option (compounded dissolvable tablets) for needle-averse patients
  • LegitScript certified

Where it loses points

  • Compounded semaglutide at $179/mo is mid-range (not the cheapest)
  • Brand-name options at near-retail pricing ($997-$1,086/mo)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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