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Head-to-head · WeighScore

Nucore Health vs Tryozi

Nucore Health
Graded #367

Lower grade

vs+2.799999999999997
Tryozi
Graded #296

Higher grade

The verdict

Tryozi takes it — 61.4/100 to 58.6/100.

Tryozi grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueTryozi +9
36
45
Dose & formulationEven
64
64
Clinical oversightNucore Health +8
82
74
Labs & monitoringNucore Health +1
53
52
FulfillmentTryozi +23
67
90
Contract termsNucore Health +6
55
49
Nucore Health · left barTryozi · right bar

The numbers

MetricNucore HealthTryozi
WeighScore58.6/10061.4/100
GradeCC
Scorecard rank#367#296
Semaglutide$299/mo (starting dose, compounded)$279/mo (compounded)
Tirzepatide$199/mo (microdose tier, compounded)$379/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Nucore Health

Graded #367 · C

Strengths

  • Physician-owned and LegitScript Certified — strong trust signals
  • Available nationwide in all 50 states
  • Care and pharmacy fulfillment run on OpenLoop Health's licensed network
  • Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12

Where it loses points

  • Published pricing is gated behind the intake quiz — no upfront cost shown
  • Legal terms and privacy are posted as downloadable documents, not web pages
  • Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
  • Longevity and microdose positioning is marketing; evidence varies by use
Tryozi

Graded #296 · C

Strengths

  • Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
  • Price does not increase as your dose increases, stated plainly on the pricing page
  • Full total shown before payment, with the first-month discount and the ongoing rate both visible
  • States plainly that compounded medications are not FDA-approved, a disclosure many competitors omit
  • LegitScript certification verified against the issued seal, not just the badge

Where it loses points

  • Headline $139 is a first-month half-price offer; the ongoing rate is $279
  • Multi-week plans are billed once as a single upfront charge, not as a lower monthly rate
  • Plans ship every 4 weeks, so a 52-week plan is 13 shipments rather than 12 months
  • No refund policy detail is published on the pricing page itself

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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