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Head-to-head · WeighScore

Nucore Health vs Sesame Care

Nucore Health
Graded #367

Lower grade

vs+29.199999999999996
Sesame Care
Graded #2

Higher grade

The verdict

Sesame Care takes it — 87.8/100 to 58.6/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSesame Care +48
36
84
Dose & formulationSesame Care +28
64
92
Clinical oversightSesame Care +12
82
94
Labs & monitoringSesame Care +31
53
84
FulfillmentSesame Care +13
67
80
Contract termsSesame Care +37
55
92
Nucore Health · left barSesame Care · right bar

The numbers

MetricNucore HealthSesame Care
WeighScore58.6/10087.8/100
GradeCB+
Scorecard rank#367#2
Semaglutide$299/mo (starting dose, compounded)From $149/mo (brand Wegovy pill)
Tirzepatide$199/mo (microdose tier, compounded)Brand Zepbound (price varies)
CoverageCoverage not publishedNationwide marketplace
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
Nucore Health

Graded #367 · C

Strengths

  • Physician-owned and LegitScript Certified — strong trust signals
  • Available nationwide in all 50 states
  • Care and pharmacy fulfillment run on OpenLoop Health's licensed network
  • Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12

Where it loses points

  • Published pricing is gated behind the intake quiz — no upfront cost shown
  • Legal terms and privacy are posted as downloadable documents, not web pages
  • Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
  • Longevity and microdose positioning is marketing; evidence varies by use
Sesame Care

Graded #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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