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Head-to-head · WeighScore

Nucific vs Tryozi

Nucific
Graded #417

Lower grade

vs+5.199999999999996
Tryozi
Graded #295

Higher grade

The verdict

Tryozi takes it — 61.4/100 to 56.2/100.

Tryozi grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulationTryozi +11
53
64
Clinical oversightNucific +2
76
74
Labs & monitoringEven
52
52
FulfillmentTryozi +23
67
90
Contract termsTryozi +8
41
49
Nucific · left barTryozi · right bar

The numbers

MetricNucificTryozi
WeighScore56.2/10061.4/100
GradeCC
Scorecard rank#417#295
SemaglutideNot disclosed$279/mo (compounded)
TirzepatideNot disclosed$379/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Nucific

Graded #417 · C

Strengths

  • Founder is named and credentialed: Dr. Amy Lee, MD, triple board-certified in Internal Medicine, Obesity Medicine and Clinical Nutrition
  • Cites SURMOUNT-1 properly, naming the trial, the 20.9% average and the Jastreboff NEJM 2022 source
  • Discloses that featured patients were compensated for their time
  • Labels its NAD+ decline chart as illustrative and not a measurement, with an unusually careful methodology note
  • Offers compounded, microdosed and brand-name Ozempic and Zepbound in one catalogue

Where it loses points

  • No price is published anywhere; every option is gated behind a three-minute quiz
  • The LegitScript badge is a self-hosted image with generic alt text rather than the issued embed, so the certification could not be verified
  • A BBB Accredited A+ claim is displayed without a link to the BBB profile
  • No state list and no named pharmacy, only licensed U.S. pharmacies
  • Before-and-after photographs are used alongside compensated testimonials
Tryozi

Graded #295 · C

Strengths

  • Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
  • Price does not increase as your dose increases, stated plainly on the pricing page
  • Full total shown before payment, with the first-month discount and the ongoing rate both visible
  • States plainly that compounded medications are not FDA-approved, a disclosure many competitors omit
  • LegitScript certification verified against the issued seal, not just the badge

Where it loses points

  • Headline $139 is a first-month half-price offer; the ongoing rate is $279
  • Multi-week plans are billed once as a single upfront charge, not as a lower monthly rate
  • Plans ship every 4 weeks, so a 52-week plan is 13 shipments rather than 12 months
  • No refund policy detail is published on the pricing page itself

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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