Head-to-head · WeighScore
Novi vs Vyora Wellness
The verdict
Vyora Wellness takes it — 60.5/100 to 59.7/100, but only just.
Vyora Wellness grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Vyora Wellness offers compounded semaglutide ($299/mo) and compounded tirzepatide ($399/mo) as 4-week subscription plans. Novi is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Novi | Vyora Wellness |
|---|---|---|
| WeighScore | 59.7/100 | 60.5/100 |
| Grade | C | C |
| Scorecard rank | #335 | #322 |
| Semaglutide | $174/mo (starting dose, compounded) | $299/mo (compounded) |
| Tirzepatide | $283/mo (starting dose, compounded) | $399/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #335 · C
Strengths
- Transparent all-in monthly pricing — medication, clinician support, and shipping bundled with no hidden fees or membership add-ons
- Both compounded semaglutide and tirzepatide available
- Unlimited clinician messaging included at no extra cost
- Free 2-day shipping on every refill
Where it loses points
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro option
- 3-month minimum commitment is non-refundable per Terms of Service unless a clinician deems treatment medically inappropriate
- State availability and pharmacy partners not publicly listed — patients learn during intake which states and pharmacies serve them
Graded #322 · C
Strengths
- LegitScript certified
- Price includes nutritional guidance, 24/7 coaching, and community access
- Both semaglutide and tirzepatide available
- BMI 25+ eligibility threshold (lower than some competitors)
Where it loses points
- State availability not publicly disclosed
- Pricing is above average ($299–$399/mo) compared to competitors
- Compounded only — no brand-name options
- Broader platform (metabolic, longevity, topical products)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.