Head-to-head · WeighScore
Nirwana Health vs PlexusDx
The verdict
PlexusDx takes it — 67.7/100 to 66.4/100, but only just.
PlexusDx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states. Nirwana Health is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Nirwana Health | PlexusDx |
|---|---|---|
| WeighScore | 66.4/100 | 67.7/100 |
| Grade | C | C |
| Scorecard rank | #186 | #158 |
| Semaglutide | $149/mo (compounded) | $149/mo (starting dose, compounded) |
| Tirzepatide | $229/mo (compounded) | $249/mo (starting dose, compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #186 · C
Strengths
- Offers compounded semaglutide and tirzepatide as both weekly injections and oral tablets
- Transparent, published pricing with month-to-month, quarterly, and 6-month plans and no membership fee
- Multi-month plans cut the per-month cost sharply (semaglutide as low as $99/mo, tirzepatide as low as $133/mo)
- Advertises a $50-off code (LOOSE50) and covers weight loss plus hair, sexual-wellness, and longevity care
- Also lists a retatrutide option and custom dosing plans for higher needs
Where it loses points
- Prescribing medical group and compounding pharmacy are not named on the site
- States of operation are not published; confirm eligibility during intake
- Says it is 'LegitScript certified' but no verifiable seal is shown, so the claim is unconfirmed
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Graded #158 · C
Strengths
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
Where it loses points
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.