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Head-to-head · WeighScore

NiceRx vs Youth & Soul

NiceRx
Graded #207

Higher grade

vs+4.499999999999993
Youth & Soul
Graded #291

Lower grade

The verdict

NiceRx takes it — 66.1/100 to 61.6/100.

NiceRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. NiceRx (NiceRx LLC) offers compounded semaglutide ($199/mo) and compounded tirzepatide ($299/mo) with first-month promos.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueYouth & Soul +20
54
74
Dose & formulationEven
64
64
Clinical oversightNiceRx +32
86
54
Labs & monitoringYouth & Soul +7
53
60
FulfillmentNiceRx +30
85
55
Contract termsNiceRx +6
55
49
NiceRx · left barYouth & Soul · right bar

The numbers

MetricNiceRxYouth & Soul
WeighScore66.1/10061.6/100
GradeCC
Scorecard rank#207#291
Semaglutide$199/mo (compounded)$149/mo (starting dose, compounded)
Tirzepatide$299/mo (compounded)$399/mo (compounded)
Coverage46 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
NiceRx

Graded #207 · C

Strengths

  • LegitScript approved
  • Named legal entity (NiceRx LLC) with Boca Raton FL address
  • First-month discount on both drugs
  • Every batch tested for sterility and potency
  • 46-state coverage

Where it loses points

  • Not available in Alaska, Mississippi, New Jersey, Kansas
  • Compounded only — no brand-name options
  • Broader platform (anti-aging, NAD+, B12)
Youth & Soul

Graded #291 · C

Strengths

  • Three GLP-1 tiers priced openly, with the dose range and every included component listed per tier
  • Full refund advertised if you are not approved
  • Physician consultation, prescription and shipping stated as included in the plan price
  • Ten treatment verticals under one account, from GLP-1 to HRT, peptides and mental health

Where it loses points

  • Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
  • Presents scraped third-party comments as testimonials, several using Reddit usernames and some describing brand Wegovy or Mounjaro
  • Its own copy promises never to fabricate testimonials while displaying those scraped comments
  • Homepage trust counters render as 0K+ medical professionals, 0.0M+ patients and 0M+ successful orders
  • Labels its compounded tirzepatide a Mounjaro compound, conflating a compounded drug with the brand

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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