Head-to-head · WeighScore
NiceRx vs Rylo Health
The verdict
NiceRx takes it — 66.1/100 to 64.7/100, but only just.
NiceRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. NiceRx (NiceRx LLC) offers compounded semaglutide ($199/mo) and compounded tirzepatide ($299/mo) with first-month promos. Rylo Health is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | NiceRx | Rylo Health |
|---|---|---|
| WeighScore | 66.1/100 | 64.7/100 |
| Grade | C | C |
| Scorecard rank | #209 | #240 |
| Semaglutide | $199/mo (compounded) | $149/mo (promotional rate, compounded) |
| Tirzepatide | $299/mo (compounded) | $249/mo (compounded) |
| Coverage | 46 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #209 · C
Strengths
- LegitScript approved
- Named legal entity (NiceRx LLC) with Boca Raton FL address
- First-month discount on both drugs
- Every batch tested for sterility and potency
- 46-state coverage
Where it loses points
- Not available in Alaska, Mississippi, New Jersey, Kansas
- Compounded only — no brand-name options
- Broader platform (anti-aging, NAD+, B12)
Graded #240 · C
Strengths
- Names its dispensing pharmacy in full, with address and phone: VialsRX in Houston, Texas
- Names its medical group, Lone Star Virtual Health PLLC, and gives a provider contact
- Standard prices published openly alongside the promotional rate, so the real ongoing cost is visible
- Cancel in one click from the patient portal, with no contracts and no cancellation fees
- Peptide line priced openly, including NAD+ and sermorelin
Where it loses points
- Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
- No LegitScript certification is claimed or displayed
- Several peptide products are advertised as coming soon rather than available
- No published refund policy beyond the no-cancellation-fee statement
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.