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Head-to-head · WeighScore

Next Vial vs Synergy Rx

Next Vial
Graded #345

Lower grade

vs+16.900000000000006
Synergy Rx
Graded #41

Higher grade

The verdict

Synergy Rx takes it — 76.2/100 to 59.3/100.

Synergy Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSynergy Rx +22
40
62
Dose & formulationSynergy Rx +36
52
88
Clinical oversightSynergy Rx +10
82
92
Labs & monitoringSynergy Rx +14
52
66
FulfillmentNext Vial +8
86
78
Contract termsSynergy Rx +13
55
68
Next Vial · left barSynergy Rx · right bar

The numbers

MetricNext VialSynergy Rx
WeighScore59.3/10076.2/100
GradeCC
Scorecard rank#345#41
Semaglutide$250/mo (compounded)From $199/mo
TirzepatideNot disclosedFrom $349/mo
Coverage49 statesNot disclosed
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Next Vial

Graded #345 · C

Strengths

  • LegitScript verified with named pharmacy partner (Manifest Pharmacy, Greer, SC)
  • No membership fees — one all-in price covering consultation, medication, and shipping
  • Compounded semaglutide, tirzepatide, and microdose options available
  • Free rushed shipping; serves 49 states nationwide
  • Board-certified physician oversight with ongoing provider support

Where it loses points

  • Tirzepatide pricing not listed publicly (starting price covers GLP-1 generally)
  • Compounded medications are not FDA-approved
  • Labs and nutritional coaching not disclosed
  • Microdose pricing not published on product page
  • Alaska not listed among served states
Synergy Rx

Graded #41 · C

Strengths

  • Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
  • Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
  • $100 welcome credit at checkout, and FSA/HSA eligible

Where it loses points

  • Publishes no GLP-1 price anywhere on its own site
  • At $349/mo tirzepatide sits roughly $100 above the compounded median we track
  • Does not publish which states it serves
  • No published cancellation or refund terms

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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