Head-to-head · WeighScore
NewSelf vs Ryze Rx
The verdict
NewSelf takes it — 85.6/100 to 58.2/100.
NewSelf grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Round-$100 semaglutide, $144 tirzepatide, verified and available in all 50 states.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | NewSelf | Ryze Rx |
|---|---|---|
| WeighScore | 85.6/100 | 58.2/100 |
| Grade | B | C |
| Scorecard rank | #18 | #376 |
| Semaglutide | $100/mo | $199/mo (starting dose, 3 month plan, compounded) |
| Tirzepatide | $144/mo | $199/mo (starting dose, 3 month plan, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #18 · B
Strengths
- $100 sema / $144 tirz
- All 50 states, LegitScript-verified
- Both molecules
Where it loses points
- Injection-only
- Labs/monitoring detail sparse
- Limited brand history
Graded #376 · C
Strengths
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
- Free shipping, 24hr prescription turnaround, FSA/HSA eligible; care advertised in all 50 states
Where it loses points
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
- Homepage advertises GLP-1s 'from $149/mo' but the catalog lists $199/mo
- On-site '4.9/5, 2,400+ reviews' is self-reported, not an independently verified rating
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.