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Head-to-head · WeighScore

Nalena vs Open Water Rx

Nalena
Graded #98

Higher grade

vs+12.400000000000006
Open Water Rx
Graded #359

Lower grade

The verdict

Nalena takes it — 71.2/100 to 58.8/100.

Nalena grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Nalena is a women-focused, GLP-1-only telehealth platform offering compounded semaglutide and tirzepatide with medication included — no separate membership or visit fees.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueNalena +26
74
48
Dose & formulationOpen Water Rx +24
64
88
Clinical oversightNalena +28
82
54
Labs & monitoringOpen Water Rx +7
53
60
FulfillmentNalena +47
89
42
Contract termsNalena +6
61
55
Nalena · left barOpen Water Rx · right bar

The numbers

MetricNalenaOpen Water Rx
WeighScore71.2/10058.8/100
GradeCC
Scorecard rank#98#359
Semaglutide$149/mo (starting dose, compounded)$249/mo (compounded)
Tirzepatide$149/mo (starting dose, compounded)$339/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
Nalena

Graded #98 · C

Strengths

  • Compounded GLP-1 from $149/mo with medication included — near the floor of the compounded market
  • Transparent fee model: no hidden fees, no membership, cancel anytime
  • Money-back guarantee — uncommon among compounded telehealths
  • Clinical provider disclosed: Beluga Health, P.A. in Houston, TX
  • Women-focused positioning

Where it loses points

  • Per-dose pricing not published — only the 'starting at $149' entry price
  • No LegitScript, HIPAA, or NABP badges on public pages
  • Compounding pharmacy partners not named (only 'multiple USA certified pharmacies')
  • Houston address looks like a virtual office rather than a clinical facility
  • No brand-name GLP-1s (Wegovy, Zepbound, Ozempic, Mounjaro) — compounded only
Open Water Rx

Graded #359 · C

Strengths

  • Combines weight-loss and longevity verticals in one brand
  • Established brand domain

Where it loses points

  • Limited public data — most details are gated behind signup or rendered only in JavaScript
  • Pricing not disclosed
  • GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
  • States-served list not disclosed
  • Pharmacy partner not named

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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