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Head-to-head · WeighScore

MyStart Health vs PCOS Sisters

MyStart Health
Graded #176

Higher grade

vs+1.3999999999999915
PCOS Sisters
Graded #218

Lower grade

The verdict

MyStart Health takes it — 67.1/100 to 65.7/100, but only just.

MyStart Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access. PCOS Sisters is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +13
48
61
Dose & formulationPCOS Sisters +5
83
88
Clinical oversightMyStart Health +14
84
70
Labs & monitoringMyStart Health +14
66
52
FulfillmentMyStart Health +13
78
65
Contract termsPCOS Sisters +10
31
41
MyStart Health · left barPCOS Sisters · right bar

The numbers

MetricMyStart HealthPCOS Sisters
WeighScore67.1/10065.7/100
GradeCC
Scorecard rank#176#218
Semaglutide$299/mo (all doses, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$299/mo (all doses, compounded)$150/mo (plus a separate fee, compounded)
CoverageCoverage not published12 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
MyStart Health

Graded #176 · C

Strengths

  • Price Lock Guarantee — your $299 base rate doesn't rise as your dose escalates
  • Fast onboarding: roughly 5-minute intake, 24-hour prescription turnaround, 2–4 day shipping
  • 24/7 care team access with unlimited clinician messaging included
  • LegitScript certified
  • Clear Section 503A compounding disclosure on every landing page

Where it loses points

  • Not BBB accredited — C+ rating with 10 complaints, mostly shipping delays and support access
  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Markets oral tirzepatide, but no FDA-approved oral tirzepatide exists
  • Very new company (incorporated May 2024) with a limited track record
  • Pharmacy partners not named, so 503A compliance can't be independently verified
PCOS Sisters

Graded #218 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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