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Head-to-head · WeighScore

Metabolyz vs Synergy Rx

Metabolyz
Graded #339

Lower grade

vs+16.6
Synergy Rx
Graded #41

Higher grade

The verdict

Synergy Rx takes it — 76.2/100 to 59.6/100.

Synergy Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSynergy Rx +17
45
62
Dose & formulationSynergy Rx +48
40
88
Clinical oversightSynergy Rx +11
81
92
Labs & monitoringSynergy Rx +3
63
66
FulfillmentMetabolyz +8
86
78
Contract termsSynergy Rx +13
55
68
Metabolyz · left barSynergy Rx · right bar

The numbers

MetricMetabolyzSynergy Rx
WeighScore59.6/10076.2/100
GradeCC
Scorecard rank#339#41
SemaglutideNot disclosedFrom $199/mo
TirzepatideNot disclosedFrom $349/mo
CoverageAll 50 statesNot disclosed
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Metabolyz

Graded #339 · C

Strengths

  • Three GLP-1 programs: standard semaglutide, dual-agonist tirzepatide, and a microdose protocol for near-goal or dose-sensitive patients
  • Nutrition, movement, and lifestyle coaching included in all programs at no extra charge
  • Medication compounded in licensed 503A/503B US pharmacies with temperature-controlled, unmarked direct-to-door delivery
  • Licensed provider supervision with direct messaging access and structured check-ins throughout
  • Telehealth across all 50 states; BMI 27+ eligibility (25+ with weight-related condition)

Where it loses points

  • Pricing is fully gated — not disclosed until after consultation, preventing upfront cost comparison
  • Compounded GLP-1 only — no brand-name options (Wegovy, Zepbound) available
  • No LegitScript certification or named medical leadership found on public-facing pages
  • Labs not mentioned as included — unclear whether baseline or follow-up bloodwork is offered
  • Newer brand with no external reviews, published outcomes data, or notable accreditations
Synergy Rx

Graded #41 · C

Strengths

  • Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate
  • Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
  • $100 welcome credit at checkout, and FSA/HSA eligible

Where it loses points

  • Publishes no GLP-1 price anywhere on its own site
  • At $349/mo tirzepatide sits roughly $100 above the compounded median we track
  • Does not publish which states it serves
  • No published cancellation or refund terms

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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