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Head-to-head · WeighScore

Medsol RX vs Tryozi

Medsol RX
Graded #306

Lower grade

vs+0.3999999999999986
Tryozi
Graded #296

Higher grade

The verdict

Tryozi takes it — 61.4/100 to 61/100, but only just.

Tryozi grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies. Medsol RX is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulationEven
64
64
Clinical oversightMedsol RX +5
79
74
Labs & monitoringMedsol RX +1
53
52
FulfillmentTryozi +7
83
90
Contract termsTryozi +8
41
49
Medsol RX · left barTryozi · right bar

The numbers

MetricMedsol RXTryozi
WeighScore61/10061.4/100
GradeCC
Scorecard rank#306#296
Semaglutide$209/mo (compounded)$279/mo (compounded)
Tirzepatide$250/mo (compounded)$379/mo (compounded)
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Medsol RX

Graded #306 · C

Strengths

  • Compounded semaglutide from $209/mo (12-mo plan) and tirzepatide from ~$250/mo; HSA/FSA eligible with Klarna financing
  • Every plan bundles the medication, a dedicated care coach, custom treatment plan, medical oversight, and free shipping
  • Board-certified clinicians via OpenLoop; same-day approvals; ships nationwide
  • Month-to-month option ($199 first month) with no long-term commitment, plus microdosing and wellness add-ons

Where it loses points

  • Doesn't name its compounding pharmacy (generic 'certified U.S. pharmacies')
  • No legal entity name published on the site
  • Tirzepatide pricing is given as a range ($250-$1,400/mo), not a fixed rate
  • Compounded GLP-1s are not FDA-approved (the site discloses this)
Tryozi

Graded #296 · C

Strengths

  • Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
  • Price does not increase as your dose increases, stated plainly on the pricing page
  • Full total shown before payment, with the first-month discount and the ongoing rate both visible
  • States plainly that compounded medications are not FDA-approved, a disclosure many competitors omit
  • LegitScript certification verified against the issued seal, not just the badge

Where it loses points

  • Headline $139 is a first-month half-price offer; the ongoing rate is $279
  • Multi-week plans are billed once as a single upfront charge, not as a lower monthly rate
  • Plans ship every 4 weeks, so a 52-week plan is 13 shipments rather than 12 months
  • No refund policy detail is published on the pricing page itself

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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