Head-to-head · WeighScore
Medsol RX vs Metabolyz
The verdict
Medsol RX takes it — 61/100 to 59.6/100, but only just.
Medsol RX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Medsol RX is a GLP-1 weight-loss telehealth program offering compounded semaglutide (from $209/mo) and tirzepatide, prescribed by board-certified clinicians via OpenLoop and shipped nationwide. Metabolyz is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Medsol RX | Metabolyz |
|---|---|---|
| WeighScore | 61/100 | 59.6/100 |
| Grade | C | C |
| Scorecard rank | #306 | #339 |
| Semaglutide | $209/mo (compounded) | Not disclosed |
| Tirzepatide | $250/mo (compounded) | Not disclosed |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #306 · C
Strengths
- Compounded semaglutide from $209/mo (12-mo plan) and tirzepatide from ~$250/mo; HSA/FSA eligible with Klarna financing
- Every plan bundles the medication, a dedicated care coach, custom treatment plan, medical oversight, and free shipping
- Board-certified clinicians via OpenLoop; same-day approvals; ships nationwide
- Month-to-month option ($199 first month) with no long-term commitment, plus microdosing and wellness add-ons
Where it loses points
- Doesn't name its compounding pharmacy (generic 'certified U.S. pharmacies')
- No legal entity name published on the site
- Tirzepatide pricing is given as a range ($250-$1,400/mo), not a fixed rate
- Compounded GLP-1s are not FDA-approved (the site discloses this)
Graded #339 · C
Strengths
- Three GLP-1 programs: standard semaglutide, dual-agonist tirzepatide, and a microdose protocol for near-goal or dose-sensitive patients
- Nutrition, movement, and lifestyle coaching included in all programs at no extra charge
- Medication compounded in licensed 503A/503B US pharmacies with temperature-controlled, unmarked direct-to-door delivery
- Licensed provider supervision with direct messaging access and structured check-ins throughout
- Telehealth across all 50 states; BMI 27+ eligibility (25+ with weight-related condition)
Where it loses points
- Pricing is fully gated — not disclosed until after consultation, preventing upfront cost comparison
- Compounded GLP-1 only — no brand-name options (Wegovy, Zepbound) available
- No LegitScript certification or named medical leadership found on public-facing pages
- Labs not mentioned as included — unclear whether baseline or follow-up bloodwork is offered
- Newer brand with no external reviews, published outcomes data, or notable accreditations
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.