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Head-to-head · WeighScore

Medro vs PCOS Sisters

Medro
Graded #256

Lower grade

vs+2.1000000000000014
PCOS Sisters
Graded #219

Higher grade

The verdict

PCOS Sisters takes it — 65.7/100 to 63.6/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +11
50
61
Dose & formulationPCOS Sisters +11
77
88
Clinical oversightMedro +1
71
70
Labs & monitoringEven
52
52
FulfillmentMedro +27
92
65
Contract termsPCOS Sisters +8
33
41
Medro · left barPCOS Sisters · right bar

The numbers

MetricMedroPCOS Sisters
WeighScore63.6/10065.7/100
GradeCC
Scorecard rank#256#219
Semaglutide$199/mo (compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$299/mo (compounded)$150/mo (plus a separate fee, compounded)
CoverageAll 50 states12 states
Brand-name accessYesYes
Oral / sublingualInjection onlyYes
Medro

Graded #256 · C

Strengths

  • Covers both compounded semaglutide and tirzepatide and can prescribe brand-name GLP-1s when clinically appropriate.
  • LegitScript-certified (seal #50716646), available in all 50 states, with tiered pricing shown before checkout.
  • No membership fee and free expedited shipping on all orders; online intake with no appointment required in many cases.
  • Prices drop with longer commitments (semaglutide to $149/mo, tirzepatide to $224/mo on a 12-month plan).

Where it loses points

  • Does not name its compounding pharmacy or its clinical partner medical group, so the fulfillment chain is not verifiable.
  • Pricing is described as illustrative and may change by dose, pharmacy availability, and eligibility — final cost shows only at checkout.
  • Very new brand (2026, trademark pending) spanning many verticals, with a short track record in GLP-1 care.
  • Compounded medications are not FDA-approved or therapeutically equivalent to Ozempic, Wegovy, Mounjaro, or Zepbound.
PCOS Sisters

Graded #219 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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