Head-to-head · WeighScore
MediRX vs VyrarX
The verdict
VyrarX takes it — 68.3/100 to 66.1/100.
VyrarX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. VyrarX is a LegitScript-certified telehealth platform offering compounded semaglutide (from $179/month) and compounded tirzepatide (from $329/month) via weekly injection, prescribed by licensed US physicians.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | MediRX | VyrarX |
|---|---|---|
| WeighScore | 66.1/100 | 68.3/100 |
| Grade | C | C |
| Scorecard rank | #206 | #156 |
| Semaglutide | $149/mo (compounded) | $179/mo (starting dose, compounded) |
| Tirzepatide | $199/mo (compounded) | $329/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #206 · C
Strengths
- LegitScript Certified — a meaningful trust signal for an online pharmacy
- Named operating entity disclosed (MediRX, Inc., Wyoming)
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Low promotional first-month pricing — semaglutide first month as low as $70
Where it loses points
- Doesn't publish the exact states it serves; telehealth rules vary by state
- Ongoing monthly price rises after the promotional first month
- Compounded semaglutide and tirzepatide injections — limited oral options
- Specific compounding pharmacies aren't named beyond the OpenLoop network
Graded #156 · C
Strengths
- LegitScript certified with active seal (ID 51177727)
- Semaglutide starting at $179/month with free shipping included
- 1:1 direct provider messaging and personalized titration plan in every plan
- Nutrition coaching included with the weight-loss program
- Provider review completed within 24 hours; no insurance required
Where it loses points
- Tirzepatide at $329/month starting is at the high end of the compounded market
- Compounding pharmacy not named on any public page
- No physician names or clinical leadership disclosed publicly
- Only 47 states covered — the 3 excluded states are not named on the site
- Labs not included in the weight-loss plan
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.