Head-to-head · WeighScore
MediRX vs SynergenX Health
The verdict
MediRX takes it — 66.1/100 to 58.4/100.
MediRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | MediRX | SynergenX Health |
|---|---|---|
| WeighScore | 66.1/100 | 58.4/100 |
| Grade | C | C |
| Scorecard rank | #206 | #374 |
| Semaglutide | $149/mo (compounded) | $150/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide | $199/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | 10 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #206 · C
Strengths
- LegitScript Certified — a meaningful trust signal for an online pharmacy
- Named operating entity disclosed (MediRX, Inc., Wyoming)
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Low promotional first-month pricing — semaglutide first month as low as $70
Where it loses points
- Doesn't publish the exact states it serves; telehealth rules vary by state
- Ongoing monthly price rises after the promotional first month
- Compounded semaglutide and tirzepatide injections — limited oral options
- Specific compounding pharmacies aren't named beyond the OpenLoop network
Graded #374 · C
Strengths
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Where it loses points
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.