Head-to-head · WeighScore
MediRX vs Shape Vantage
The verdict
MediRX takes it — 66.1/100 to 43/100.
MediRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | MediRX | Shape Vantage |
|---|---|---|
| WeighScore | 66.1/100 | 43/100 |
| Grade | C | C |
| Scorecard rank | #206 | #499 |
| Semaglutide | $149/mo (compounded) | Not disclosed |
| Tirzepatide | $199/mo (compounded) | $599/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #206 · C
Strengths
- LegitScript Certified — a meaningful trust signal for an online pharmacy
- Named operating entity disclosed (MediRX, Inc., Wyoming)
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Low promotional first-month pricing — semaglutide first month as low as $70
Where it loses points
- Doesn't publish the exact states it serves; telehealth rules vary by state
- Ongoing monthly price rises after the promotional first month
- Compounded semaglutide and tirzepatide injections — limited oral options
- Specific compounding pharmacies aren't named beyond the OpenLoop network
Graded #499 · C
Strengths
- $599 product price shown publicly, not gated behind intake
- Terms of Service exists and discloses the legal relationship
- Positions itself as 'Premium Weight Loss Treatment'
Where it loses points
- Homepage uses a dietary-supplement-style disclaimer, not language seen on legitimate prescription products
- Links straight to a Stripe checkout with no medical intake, consultation, or prescription gate
- Terms reserve the option to ship without prescription or provider review where not legally required
- No LegitScript, NABP, state-pharmacy, or PCAB accreditation visible
- Legal entity and state of incorporation not disclosed (only California governing law)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.