Head-to-head · WeighScore
MediRX vs Primary Clinic (Direct GLP)
The verdict
MediRX takes it — 66.1/100 to 65.5/100, but only just.
MediRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option. Primary Clinic (Direct GLP) is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | MediRX | Primary Clinic (Direct GLP) |
|---|---|---|
| WeighScore | 66.1/100 | 65.5/100 |
| Grade | C | C |
| Scorecard rank | #206 | #219 |
| Semaglutide | $149/mo (compounded) | $85/mo (0.25-0.75 mg band, membership required, compounded) |
| Tirzepatide | $199/mo (compounded) | $133/mo (1.25-2.5 mg band, membership required, compounded) |
| Coverage | Coverage not published | 10 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #206 · C
Strengths
- LegitScript Certified — a meaningful trust signal for an online pharmacy
- Named operating entity disclosed (MediRX, Inc., Wyoming)
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Low promotional first-month pricing — semaglutide first month as low as $70
Where it loses points
- Doesn't publish the exact states it serves; telehealth rules vary by state
- Ongoing monthly price rises after the promotional first month
- Compounded semaglutide and tirzepatide injections — limited oral options
- Specific compounding pharmacies aren't named beyond the OpenLoop network
Graded #219 · C
Strengths
- Direct Primary Care model integrates GLP-1 with continuous primary care — unlike most direct-to-consumer platforms
- GLP-1 at wholesale cost with no markup — semaglutide from $65/mo, tirzepatide from $110/mo (members only)
- Unlimited primary care visits, direct text access, and same-day care bundled in the $89/mo membership
- Routine labs and thousands of medications included in membership — no surprise bills
- Per-dose pricing shown publicly for all 8 dose tiers of both semaglutide and tirzepatide
Where it loses points
- The medication price is on top of an $89/mo direct-primary-care membership, which the FAQ states does not include the drug — all-in is about $174/mo for semaglutide and $222/mo for tirzepatide
- Prices are published as dose BANDS rather than per dose, and the cheapest tirzepatide band starts at 1.25 mg, below the 2.5 mg labelled starting dose
- The pricing is rendered entirely in JavaScript, so nothing on the page is readable without running the site's bundle
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.