Head-to-head · WeighScore
MediRX vs Metabolyz
The verdict
MediRX takes it — 66.1/100 to 59.6/100.
MediRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | MediRX | Metabolyz |
|---|---|---|
| WeighScore | 66.1/100 | 59.6/100 |
| Grade | C | C |
| Scorecard rank | #206 | #339 |
| Semaglutide | $149/mo (compounded) | Not disclosed |
| Tirzepatide | $199/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #206 · C
Strengths
- LegitScript Certified — a meaningful trust signal for an online pharmacy
- Named operating entity disclosed (MediRX, Inc., Wyoming)
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Low promotional first-month pricing — semaglutide first month as low as $70
Where it loses points
- Doesn't publish the exact states it serves; telehealth rules vary by state
- Ongoing monthly price rises after the promotional first month
- Compounded semaglutide and tirzepatide injections — limited oral options
- Specific compounding pharmacies aren't named beyond the OpenLoop network
Graded #339 · C
Strengths
- Three GLP-1 programs: standard semaglutide, dual-agonist tirzepatide, and a microdose protocol for near-goal or dose-sensitive patients
- Nutrition, movement, and lifestyle coaching included in all programs at no extra charge
- Medication compounded in licensed 503A/503B US pharmacies with temperature-controlled, unmarked direct-to-door delivery
- Licensed provider supervision with direct messaging access and structured check-ins throughout
- Telehealth across all 50 states; BMI 27+ eligibility (25+ with weight-related condition)
Where it loses points
- Pricing is fully gated — not disclosed until after consultation, preventing upfront cost comparison
- Compounded GLP-1 only — no brand-name options (Wegovy, Zepbound) available
- No LegitScript certification or named medical leadership found on public-facing pages
- Labs not mentioned as included — unclear whether baseline or follow-up bloodwork is offered
- Newer brand with no external reviews, published outcomes data, or notable accreditations
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.