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Head-to-head · WeighScore

Medi-Weightloss vs PlexusDx

Medi-Weightloss
Graded #124

Higher grade

vs+1.8999999999999915
PlexusDx
Graded #161

Lower grade

The verdict

Medi-Weightloss takes it — 69.6/100 to 67.7/100, but only just.

Medi-Weightloss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Medi-Weightloss is an established physician-supervised weight-loss brand with 130-plus locations nationwide plus telehealth. PlexusDx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePlexusDx +20
54
74
Dose & formulationMedi-Weightloss +1
65
64
Clinical oversightMedi-Weightloss +13
87
74
Labs & monitoringMedi-Weightloss +38
90
52
FulfillmentPlexusDx +13
65
78
Contract termsEven
55
55
Medi-Weightloss · left barPlexusDx · right bar

The numbers

MetricMedi-WeightlossPlexusDx
WeighScore69.6/10067.7/100
GradeCC
Scorecard rank#124#161
Semaglutide$199/mo (promotional rate, brand-name)$149/mo (starting dose, compounded)
TirzepatideNot disclosed$249/mo (starting dose, compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Medi-Weightloss

Graded #124 · C

Strengths

  • Both branded (Wegovy, Zepbound) and compounded semaglutide/tirzepatide
  • Established brand with 130+ physician-supervised locations nationwide
  • Telehealth plus in-person clinic options
  • Accepts insurance at many locations; HSA/FSA welcome
  • Includes body-composition analysis and personalized plans

Where it loses points

  • Ongoing medication pricing not transparently posted; varies by plan
  • $199 new-patient visit fee before medication costs
  • Frequent (often weekly) visits expected for some patients
  • Compounded products are not FDA-approved or evaluated
PlexusDx

Graded #161 · C

Strengths

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Where it loses points

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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