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Head-to-head · WeighScore

MD Trim Clinic vs PCOS Sisters

MD Trim Clinic
Graded #421

Lower grade

vs+9.899999999999999
PCOS Sisters
Graded #211

Higher grade

The verdict

PCOS Sisters takes it — 66/100 to 56.1/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +17
45
62
Dose & formulationPCOS Sisters +48
40
88
Clinical oversightMD Trim Clinic +10
80
70
Labs & monitoringMD Trim Clinic +11
63
52
FulfillmentPCOS Sisters +7
58
65
Contract termsMD Trim Clinic +14
55
41
MD Trim Clinic · left barPCOS Sisters · right bar

The numbers

MetricMD Trim ClinicPCOS Sisters
WeighScore56.1/10066/100
GradeCC
Scorecard rank#421#211
SemaglutideNot disclosed$150/mo (plus a separate fee, compounded)
TirzepatideNot disclosed$150/mo (plus a separate fee, compounded)
Coverage2 states12 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
MD Trim Clinic

Graded #421 · C

Strengths

  • Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
  • Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
  • Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
  • Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
  • Partnered mobile IV services available for enhanced nausea management and hydration support

Where it loses points

  • Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
  • Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
  • No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
  • Small practice with limited online presence and no published patient reviews or outcomes data
  • No labs, coaching, or monitoring protocols disclosed on the site
PCOS Sisters

Graded #211 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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