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Head-to-head · WeighScore

MANÜ Telehealth vs Silhouette MD

MANÜ Telehealth
Graded #86

Higher grade

vs+2.5999999999999943
Silhouette MD
Graded #129

Lower grade

The verdict

MANÜ Telehealth takes it — 72/100 to 69.4/100.

MANÜ Telehealth grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MANÜ Telehealth is a US online platform offering compounded GLP-1 weight loss medication including injectable tirzepatide and semaglutide, with add-ons like MIC Ultraburn and NAD+ injections.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueMANÜ Telehealth +10
84
74
Dose & formulationSilhouette MD +11
64
75
Clinical oversightMANÜ Telehealth +2
79
77
Labs & monitoringMANÜ Telehealth +9
63
54
FulfillmentMANÜ Telehealth +4
71
67
Contract termsEven
55
55
MANÜ Telehealth · left barSilhouette MD · right bar

The numbers

MetricMANÜ TelehealthSilhouette MD
WeighScore72/10069.4/100
GradeCC
Scorecard rank#86#129
Semaglutide$120/mo (compounded)$149/mo (compounded)
Tirzepatide$150/mo (compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
MANÜ Telehealth

Graded #86 · C

Strengths

  • Compounded GLP-1s advertised from about $4-$5/day
  • 100% online with free discreet shipping and no insurance needed
  • Compounds exclusively from US 503A pharmacies
  • Add-on options like MIC Ultraburn and NAD+

Where it loses points

  • Per-dose pricing is gated behind login/signup, not public
  • State availability changes and is only confirmed at signup
  • Compounded medications are not FDA-evaluated
Silhouette MD

Graded #129 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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