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Head-to-head · WeighScore

MANÜ Telehealth vs Rylo Health

MANÜ Telehealth
Graded #83

Higher grade

vs+7.5
Rylo Health
Graded #236

Lower grade

The verdict

MANÜ Telehealth takes it — 72.2/100 to 64.7/100.

MANÜ Telehealth grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MANÜ Telehealth is a US online platform offering compounded GLP-1 weight loss medication including injectable tirzepatide and semaglutide, with add-ons like MIC Ultraburn and NAD+ injections.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueMANÜ Telehealth +21
85
64
Dose & formulationEven
64
64
Clinical oversightMANÜ Telehealth +4
79
75
Labs & monitoringMANÜ Telehealth +10
63
53
FulfillmentRylo Health +12
71
83
Contract termsMANÜ Telehealth +18
55
37
MANÜ Telehealth · left barRylo Health · right bar

The numbers

MetricMANÜ TelehealthRylo Health
WeighScore72.2/10064.7/100
GradeCC
Scorecard rank#83#236
Semaglutide$120/mo (compounded)$149/mo (promotional rate, compounded)
Tirzepatide$150/mo (compounded)$249/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
MANÜ Telehealth

Graded #83 · C

Strengths

  • Compounded GLP-1s advertised from about $4-$5/day
  • 100% online with free discreet shipping and no insurance needed
  • Compounds exclusively from US 503A pharmacies
  • Add-on options like MIC Ultraburn and NAD+

Where it loses points

  • Per-dose pricing is gated behind login/signup, not public
  • State availability changes and is only confirmed at signup
  • Compounded medications are not FDA-evaluated
Rylo Health

Graded #236 · C

Strengths

  • Names its dispensing pharmacy in full, with address and phone: VialsRX in Houston, Texas
  • Names its medical group, Lone Star Virtual Health PLLC, and gives a provider contact
  • Standard prices published openly alongside the promotional rate, so the real ongoing cost is visible
  • Cancel in one click from the patient portal, with no contracts and no cancellation fees
  • Peptide line priced openly, including NAD+ and sermorelin

Where it loses points

  • Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
  • No LegitScript certification is claimed or displayed
  • Several peptide products are advertised as coming soon rather than available
  • No published refund policy beyond the no-cancellation-fee statement

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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