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Head-to-head · WeighScore

MadeMed vs Open Water Rx

MadeMed
Graded #30

Higher grade

vs+21.60000000000001
Open Water Rx
Graded #359

Lower grade

The verdict

MadeMed takes it — 80.4/100 to 58.8/100.

MadeMed grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Publishes its price at every single dose, so what a titrated dose costs is knowable on day one.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueMadeMed +26
74
48
Dose & formulationMadeMed +2
90
88
Clinical oversightMadeMed +30
84
54
Labs & monitoringMadeMed +2
62
60
FulfillmentMadeMed +48
90
42
Contract termsMadeMed +33
88
55
MadeMed · left barOpen Water Rx · right bar

The numbers

MetricMadeMedOpen Water Rx
WeighScore80.4/10058.8/100
GradeB−C
Scorecard rank#30#359
Semaglutide$239/mo quarterly (from $199/mo on 6 months)$249/mo (compounded)
Tirzepatide$399/mo quarterly (from $369/mo on 6 months)$339/mo (compounded)
Coverage40 statesCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
MadeMed

Graded #30 · B−

Strengths

  • One flat price at every dose, published dose by dose — semaglutide 0.25–2.4mg, tirzepatide 2.5–15mg
  • LegitScript verified, with board-certified physician review and US compounding pharmacies
  • Full refund minus a $39 visit fee if you are not prescribed, stated before checkout
  • Oral semaglutide and oral tirzepatide alongside the injections; free overnight shipping with supplies

Where it loses points

  • The most expensive tirzepatide here at $399/mo quarterly
  • 40 states rather than nationwide
  • No published recurring lab programme
  • Ships one vial every two months, a less flexible cadence than a monthly refill
Open Water Rx

Graded #359 · C

Strengths

  • Combines weight-loss and longevity verticals in one brand
  • Established brand domain

Where it loses points

  • Limited public data — most details are gated behind signup or rendered only in JavaScript
  • Pricing not disclosed
  • GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
  • States-served list not disclosed
  • Pharmacy partner not named

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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