Head-to-head · WeighScore
MadeMed vs Direct Meds
The verdict
Direct Meds takes it — 82.6/100 to 80.4/100.
Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.
We may earn a commission if you start care through some of these links, at no extra cost to you. Affiliate partners are listed first — a capped 3-point edge in board order only. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | MadeMed | Direct Meds |
|---|---|---|
| WeighScore | 80.4/100 | 82.6/100 |
| Grade | B− | B− |
| Scorecard rank | #29 | #18 |
| Semaglutide | $239/mo quarterly (from $199/mo on 6 months) | $179/mo |
| Tirzepatide | $399/mo quarterly (from $369/mo on 6 months) | $224/mo |
| Coverage | 40 states | Not publicly listed |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #29 · B−
Strengths
- One flat price at every dose, published dose by dose — semaglutide 0.25–2.4mg, tirzepatide 2.5–15mg
- LegitScript verified, with board-certified physician review and US compounding pharmacies
- Full refund minus a $39 visit fee if you are not prescribed, stated before checkout
- Oral semaglutide and oral tirzepatide alongside the injections; free overnight shipping with supplies
Where it loses points
- The most expensive tirzepatide here at $399/mo quarterly
- 40 states rather than nationwide
- No published recurring lab programme
- Ships one vial every two months, a less flexible cadence than a monthly refill
Graded #18 · B−
Strengths
- Rare oral/sublingual option in addition to injectable
- All-inclusive pricing with no separate membership fee
- Both molecules — semaglutide and tirzepatide
- Intro promotional pricing near $147
Where it loses points
- Compounded only — not FDA-approved
- Pricing is company-stated, not independently live-verified
- Newer and somewhat ambiguous (operates across multiple domains)
- States served are not disclosed
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 43 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.