Head-to-head · WeighScore
Lyfe Rx vs Zera Health
The verdict
Zera Health takes it — 74.8/100 to 58.3/100.
Zera Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Zera Health is a telehealth platform for compounded GLP-1 weight loss — semaglutide from $149/mo, tirzepatide from $199/mo, plus oral and low-dose microdose options — prescribed by licensed physicians in…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | Zera Health |
|---|---|---|
| WeighScore | 58.3/100 | 74.8/100 |
| Grade | C | C |
| Scorecard rank | #375 | #63 |
| Semaglutide | $225/mo (compounded) | $149/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $199/mo (compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #63 · C
Strengths
- Compounded semaglutide from $149/mo and tirzepatide from $199/mo, plus a $129/mo microdose option
- Flat pricing — the same monthly cost at every dose as you titrate up
- All-inclusive: medication, unlimited 24/7 provider messaging, and free shipping bundled in
- Names its compounding pharmacy — Strive Pharmacy (licensed 503A)
- Available in all 50 states with same-day approvals
Where it loses points
- Operates as a technology platform, not the medical provider itself
- Compounded GLP-1s are not FDA-approved (the site discloses this honestly)
- Aggressive marketing results claims (e.g. '18% average', '93% kept it off') with 'results not typical' disclaimers
- Legal entity name not published (footer shows only 'Zera Health')
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.