Head-to-head · WeighScore
Lyfe Rx vs Zappy Health
The verdict
Zappy Health takes it — 66.2/100 to 58.3/100.
Zappy Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Zappy Health is a telehealth weight-loss platform offering both compounded and brand-name GLP-1: compounded semaglutide from $159/month and tirzepatide from $299/month, plus brand Wegovy and Zepbound.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | Zappy Health |
|---|---|---|
| WeighScore | 58.3/100 | 66.2/100 |
| Grade | C | C |
| Scorecard rank | #375 | #198 |
| Semaglutide | $225/mo (compounded) | $159/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $299/mo (compounded) |
| Coverage | Coverage not published | 42 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #198 · C
Strengths
- Both compounded GLP-1 and brand-name Wegovy/Zepbound available
- Flat pricing that doesn't increase as your dose goes up
- Cheaper on longer subscriptions — compounded semaglutide from $159/month
- Online visit with a licensed clinician; no insurance required
Where it loses points
- Third-party reports of an order arriving with an unlicensed-pharmacy label
- Not available in 8 states (HI, AL, AR, CA, KS, MI, MN, MS)
- Operating legal entity isn't clearly disclosed on the site
- Lowest prices require a 9-month commitment
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.