Head-to-head · WeighScore
Lyfe Rx vs WellMedRx
The verdict
Lyfe Rx takes it — 58.3/100 to 54.5/100.
Lyfe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | WellMedRx |
|---|---|---|
| WeighScore | 58.3/100 | 54.5/100 |
| Grade | C | C |
| Scorecard rank | #375 | #456 |
| Semaglutide | $225/mo (compounded) | Not disclosed |
| Tirzepatide | $299/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #456 · C
Strengths
- Named licensed pharmacy partner (Mycelium Pharmacy)
- Clinical care delivered through OpenLoop Health, an established clinician network
- Multi-product platform — one account covers weight loss, TRT, hair, and sexual health
- HIPAA-compliant badge on the home page
Where it loses points
- Monthly pricing not shown until after intake
- State coverage not disclosed — only 'a licensed professional in your state'
- No LegitScript registration visible on the home page
- No NABP .pharmacy seal
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.