Skip to content
GLP-1 Scorecard
Menu

Head-to-head · WeighScore

Lyfe Rx vs tru Weight Loss

Lyfe Rx
Graded #375

Lower grade

vs+0.6000000000000014
tru Weight Loss
Graded #356

Higher grade

The verdict

tru Weight Loss takes it — 58.9/100 to 58.3/100, but only just.

tru Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. tru Weight Loss (truhealthnow) is a physician-directed telehealth program prescribing compounded semaglutide and tirzepatide, shipped from US-licensed compounding pharmacies. Lyfe Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLyfe Rx +12
50
38
Dose & formulationtru Weight Loss +8
64
72
Clinical oversighttru Weight Loss +9
67
76
Labs & monitoringtru Weight Loss +20
52
72
FulfillmentEven
62
62
Contract termsLyfe Rx +35
55
20
Lyfe Rx · left bartru Weight Loss · right bar

The numbers

MetricLyfe Rxtru Weight Loss
WeighScore58.3/10058.9/100
GradeCC
Scorecard rank#375#356
Semaglutide$225/mo (compounded)$299/mo (all doses, 3-month plan, compounded)
Tirzepatide$299/mo (compounded)$399/mo (all doses, 3-month plan, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
tru Weight Loss

Graded #356 · C

Strengths

  • Flat, transparent pricing (299/mo semaglutide, 399/mo tirzepatide)
  • All-inclusive: consult, lab work, medication delivery, nutritionist and behavioral coaching
  • Directed by a named physician (Neha Grover, MD) from a physical clinic

Where it loses points

  • Requires a 3-month commitment before you can cancel
  • States served are not specified and the dispensing pharmacy is not named
  • Does not accept insurance, HSA, or FSA

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

← Back to the scorecard