Head-to-head · WeighScore
Lyfe Rx vs Rex MD
The verdict
Rex MD takes it — 70.2/100 to 58.3/100.
Rex MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Rex MD is a US-based men's-health telehealth platform (a LifeMD brand) offering a 100 percent online GLP-1 weight-management program.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | Rex MD |
|---|---|---|
| WeighScore | 58.3/100 | 70.2/100 |
| Grade | C | C |
| Scorecard rank | #375 | #109 |
| Semaglutide | $225/mo (compounded) | $199/mo (brand-name) |
| Tirzepatide | $299/mo (compounded) | $349/mo (brand Zepbound) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #109 · C
Strengths
- Flat $199/mo program bundles consult, medication and overnight shipping
- Brand-name semaglutide and Zepbound vials, not just compounded
- Serves all 50 states, fully online
- LegitScript certified with US-based, state-licensed providers
- Backed by parent company LifeMD
Where it loses points
- Does not accept insurance
- Marketed primarily to men via a men's-health platform
- Zepbound vial cost rises with dose titration
- Branded-only program costs more than compounded options
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.