Head-to-head · WeighScore
Lyfe Rx vs Refills
The verdict
Lyfe Rx takes it — 58.3/100 to 55.2/100.
Lyfe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | Refills |
|---|---|---|
| WeighScore | 58.3/100 | 55.2/100 |
| Grade | C | C |
| Scorecard rank | #375 | #443 |
| Semaglutide | $225/mo (compounded) | Not disclosed |
| Tirzepatide | $299/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #443 · C
Strengths
- LegitScript Certified online pharmacy
- Claims operation across all 50 states (with some exclusions)
- Multi-category platform (weight loss + ED + hair growth + wellness) — single account for multiple treatments
- Free shipping disclosed publicly
- Cash-pay, no insurance needed
Where it loses points
- Ongoing monthly pricing for compounded semaglutide and tirzepatide not shown until after intake
- Legal entity name and state of incorporation not disclosed
- Compounding pharmacy partner not named
- Excluded states not listed in marketing copy — verify coverage during intake
- Compounded only — no brand-name GLP-1 (Wegovy, Zepbound, Mounjaro, Ozempic, Foundayo)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.