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Head-to-head · WeighScore

Lyfe Rx vs RedBox Rx

Lyfe Rx
Graded #375

Lower grade

vs+11.900000000000006
RedBox Rx
Graded #108

Higher grade

The verdict

RedBox Rx takes it — 70.2/100 to 58.3/100.

RedBox Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. RedBox Rx is a US telehealth pharmacy (parent company Hy-Vee) offering compounded GLP-1 weight management with flat, dose-independent pricing.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLyfe Rx +8
50
42
Dose & formulationRedBox Rx +19
64
83
Clinical oversightRedBox Rx +26
67
93
Labs & monitoringRedBox Rx +32
52
84
FulfillmentRedBox Rx +10
62
72
Contract termsLyfe Rx +14
55
41
Lyfe Rx · left barRedBox Rx · right bar

The numbers

MetricLyfe RxRedBox Rx
WeighScore58.3/10070.2/100
GradeCC
Scorecard rank#375#108
Semaglutide$225/mo (compounded)$269/mo (all doses, 6-month plan, compounded)
Tirzepatide$299/mo (compounded)$429/mo
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
RedBox Rx

Graded #108 · C

Strengths

  • Flat, dose-independent pricing on both semaglutide and tirzepatide
  • Offers both weekly injections and daily oral tablets
  • Includes unlimited provider follow-ups, a metabolic panel and a dietitian session
  • Backed by grocery-pharmacy parent company Hy-Vee

Where it loses points

  • Does not serve every state (for example Mississippi is excluded)
  • Does not publicly name its compounding pharmacy

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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