Head-to-head · WeighScore
Lyfe Rx vs Prime Health
The verdict
Prime Health takes it — 59.4/100 to 58.3/100, but only just.
Prime Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Prime Health (joinprimehealth.com) is a LegitScript-certified GLP-1 telehealth platform offering compounded semaglutide and tirzepatide for weight loss. Lyfe Rx is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | Prime Health |
|---|---|---|
| WeighScore | 58.3/100 | 59.4/100 |
| Grade | C | C |
| Scorecard rank | #375 | #344 |
| Semaglutide | $225/mo (compounded) | $299/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $399/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #344 · C
Strengths
- LegitScript-certified platform
- Flat pricing that does not rise as dosage increases
- Bundle includes medication, labs, shipping, and unlimited clinician access
- Money-back guarantee of at least 10% body-weight loss in 4 months
- Fast 24-hour prescription review and 5-7 day delivery
Where it loses points
- Compounded medications only; no FDA-approved brand options listed
- Not available in Louisiana
- Care delivered through third-party clinician groups, not in-house
- Named compounding pharmacy not disclosed
- No insurance accepted
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.