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Head-to-head · WeighScore

Lyfe Rx vs PrescribedRX

Lyfe Rx
Graded #375

Lower grade

vs+0.7000000000000028
PrescribedRX
Graded #351

Higher grade

The verdict

PrescribedRX takes it — 59/100 to 58.3/100, but only just.

PrescribedRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PrescribedRX is a multi-condition telehealth brand (TRT, longevity, hair loss, sexual health and weight loss) that prescribes compounded GLP-1 injectables for weight loss: semaglutide at $189/month and… Lyfe Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLyfe Rx +3
50
47
Dose & formulationPrescribedRX +13
64
77
Clinical oversightPrescribedRX +7
67
74
Labs & monitoringEven
52
52
FulfillmentPrescribedRX +2
62
64
Contract termsLyfe Rx +35
55
20
Lyfe Rx · left barPrescribedRX · right bar

The numbers

MetricLyfe RxPrescribedRX
WeighScore58.3/10059/100
GradeCC
Scorecard rank#375#351
Semaglutide$225/mo (compounded)$189/mo (compounded)
Tirzepatide$299/mo (compounded)$276/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
PrescribedRX

Graded #351 · C

Strengths

  • Compounded semaglutide ($189/mo) and tirzepatide ($276/mo) injectables, with lower per-month pricing on the 3-month plans ($176 and $233/mo)
  • Clear, upfront plan pages showing monthly and multi-month pricing with no surprise fees
  • Care from licensed US providers with monthly home delivery and ongoing dose support
  • Bilingual English/Spanish site and a broader telehealth menu (TRT, longevity, hair, sexual health) for people who want more than weight loss

Where it loses points

  • Doesn't publish the states it serves — you only learn eligibility after starting the intake
  • Compounding pharmacies aren't named on the site
  • Mid-range pricing — cheaper compounded GLP-1 options exist and the 3-month discount is modest
  • Compounded semaglutide and tirzepatide injectables only — no brand-name or oral options
  • Self-hosted affiliate program (not a vetted network); Florida/Palm Beach framing suggests a regional lean

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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