Head-to-head · WeighScore
Lyfe Rx vs Peptivo
The verdict
Peptivo takes it — 60.1/100 to 58.3/100, but only just.
Peptivo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Peptivo is a 100% online GLP-1 weight-loss telehealth service offering compounded medication made in the USA at FDA-registered labs, with same-day provider visits and 24/7 messaging. Lyfe Rx is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | Peptivo |
|---|---|---|
| WeighScore | 58.3/100 | 60.1/100 |
| Grade | C | C |
| Scorecard rank | #375 | #330 |
| Semaglutide | $225/mo (compounded) | Not disclosed |
| Tirzepatide | $299/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #330 · C
Strengths
- Low entry pricing — GLP-1 weight-loss plans starting at $169/mo, with free discreet shipping
- Same-day provider visits and 24/7 provider messaging; 100% online
- Compounded in the USA at FDA-registered labs; can also prescribe brand GLP-1 (Ozempic, Wegovy, Zepbound)
- FSA/HSA eligible with upfront pricing
Where it loses points
- GLP-1 products use generic names ('GLP-1 Daily Support', 'Weight Loss Boost') — semaglutide/tirzepatide not clearly broken out
- Compounding pharmacy/lab partner not named
- Limited published policies (privacy and terms only; no HIPAA notice or refund policy found)
- Not LegitScript-certified (no certification displayed)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.