Head-to-head · WeighScore
Lyfe Rx vs Medi-Weightloss
The verdict
Medi-Weightloss takes it — 69.6/100 to 58.3/100.
Medi-Weightloss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Medi-Weightloss is an established physician-supervised weight-loss brand with 130-plus locations nationwide plus telehealth.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | Medi-Weightloss |
|---|---|---|
| WeighScore | 58.3/100 | 69.6/100 |
| Grade | C | C |
| Scorecard rank | #375 | #118 |
| Semaglutide | $225/mo (compounded) | $199/mo (promotional rate, brand-name) |
| Tirzepatide | $299/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #118 · C
Strengths
- Both branded (Wegovy, Zepbound) and compounded semaglutide/tirzepatide
- Established brand with 130+ physician-supervised locations nationwide
- Telehealth plus in-person clinic options
- Accepts insurance at many locations; HSA/FSA welcome
- Includes body-composition analysis and personalized plans
Where it loses points
- Ongoing medication pricing not transparently posted; varies by plan
- $199 new-patient visit fee before medication costs
- Frequent (often weekly) visits expected for some patients
- Compounded products are not FDA-approved or evaluated
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.