Head-to-head · WeighScore
Lyfe Rx vs MANÜ Telehealth
The verdict
MANÜ Telehealth takes it — 72.2/100 to 58.3/100.
MANÜ Telehealth grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MANÜ Telehealth is a US online platform offering compounded GLP-1 weight loss medication including injectable tirzepatide and semaglutide, with add-ons like MIC Ultraburn and NAD+ injections.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Lyfe Rx | MANÜ Telehealth |
|---|---|---|
| WeighScore | 58.3/100 | 72.2/100 |
| Grade | C | C |
| Scorecard rank | #375 | #83 |
| Semaglutide | $225/mo (compounded) | $120/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $150/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Graded #83 · C
Strengths
- Compounded GLP-1s advertised from about $4-$5/day
- 100% online with free discreet shipping and no insurance needed
- Compounds exclusively from US 503A pharmacies
- Add-on options like MIC Ultraburn and NAD+
Where it loses points
- Per-dose pricing is gated behind login/signup, not public
- State availability changes and is only confirmed at signup
- Compounded medications are not FDA-evaluated
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.