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Head-to-head · WeighScore

Luma Meds vs SkyRx

Luma Meds
Graded #391

Lower grade

vs+1.1000000000000014
SkyRx
Graded #353

Higher grade

The verdict

SkyRx takes it — 58.9/100 to 57.8/100, but only just.

SkyRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon. Luma Meds is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSkyRx +24
32
56
Dose & formulationSkyRx +7
64
71
Clinical oversightLuma Meds +22
90
68
Labs & monitoringLuma Meds +3
55
52
FulfillmentLuma Meds +12
76
64
Contract termsEven
20
20
Luma Meds · left barSkyRx · right bar

The numbers

MetricLuma MedsSkyRx
WeighScore57.8/10058.9/100
GradeCC
Scorecard rank#391#353
Semaglutide$249/mo (compounded)$199/mo (all doses, 12-month plan, compounded)
Tirzepatide$299/mo (compounded)Not disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Luma Meds

Graded #391 · C

Strengths

  • LegitScript certified — a credibility mark fewer compounded GLP-1 providers carry
  • Free discreet shipping and unlimited 24/7 support on every plan
  • Compounded semaglutide and tirzepatide from FDA-regulated 503A/503B pharmacies
  • '100,000+ members treated' claim with physician-supervised online care
  • 3-month bundle pricing brings semaglutide as low as $140/mo

Where it loses points

  • Compounding pharmacy partner not publicly named
  • States available not published
  • Monthly semaglutide ($249/mo) is above many lower-cost compounded competitors
  • No oral formulation options listed
  • Compounded medications are not FDA-approved
SkyRx

Graded #353 · C

Strengths

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Where it loses points

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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