Head-to-head · WeighScore
Luma Meds vs Lyfe Rx
The verdict
Lyfe Rx takes it — 58.3/100 to 57.8/100, but only just.
Lyfe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399). Luma Meds is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Luma Meds | Lyfe Rx |
|---|---|---|
| WeighScore | 57.8/100 | 58.3/100 |
| Grade | C | C |
| Scorecard rank | #391 | #375 |
| Semaglutide | $249/mo (compounded) | $225/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $299/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #391 · C
Strengths
- LegitScript certified — a credibility mark fewer compounded GLP-1 providers carry
- Free discreet shipping and unlimited 24/7 support on every plan
- Compounded semaglutide and tirzepatide from FDA-regulated 503A/503B pharmacies
- '100,000+ members treated' claim with physician-supervised online care
- 3-month bundle pricing brings semaglutide as low as $140/mo
Where it loses points
- Compounding pharmacy partner not publicly named
- States available not published
- Monthly semaglutide ($249/mo) is above many lower-cost compounded competitors
- No oral formulation options listed
- Compounded medications are not FDA-approved
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.