Head-to-head · WeighScore
Luma Health Co vs PCOS Sisters
The verdict
Luma Health Co takes it — 75/100 to 66/100.
Luma Health Co grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Luma Health Co is a nurse-practitioner-led virtual weight-loss and wellness clinic founded by Tiffani McKnight, FNP-C.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Luma Health Co | PCOS Sisters |
|---|---|---|
| WeighScore | 75/100 | 66/100 |
| Grade | C | C |
| Scorecard rank | #59 | #211 |
| Semaglutide | $120/mo (plus a separate fee, compounded) | $150/mo (plus a separate fee, compounded) |
| Tirzepatide | $180/mo (compounded) | $150/mo (plus a separate fee, compounded) |
| Coverage | 30 states | 12 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #59 · C
Strengths
- Transparent, competitive pricing published up front — compounded semaglutide from $120/mo, tirzepatide from $180/mo, retatrutide from $170/mo
- No subscription, monthly fee or membership — a direct-to-patient model where you pay per medication, and follow-up visits are free
- Free initial consults for first responders, law enforcement, military, nurses and teachers ($0), and $25 for other healthcare workers
- Founded and led by a named family nurse practitioner (Tiffani McKnight, FNP-C) licensed across 30 states/DC, with HIPAA-compliant virtual visits
- HSA/FSA funds and financing accepted, with itemized invoices for HSA/FSA submission
Where it loses points
- Offers compounded retatrutide (labeled "RTT/GLP-3"), an investigational triple agonist not FDA-approved — a higher-risk, less-studied option
- Compounded medications only — no brand-name Wegovy, Zepbound or Ozempic — and compounded GLP-1s aren't FDA-reviewed or approved
- No LegitScript certification shown and no compounding-pharmacy partner named, so the dispensing pharmacy can't be independently verified
- Small, newly established founder-led practice with a thin website and limited public track record or third-party reviews
- Medication prices are "starting at" and billed on top of a one-time consult fee, so the true first-month cost runs higher than the headline
Graded #211 · C
Strengths
- Dedicated PCOS specialty model with metabolic program and fitness app included
- Transparent 150 dollars per month GLP-1 management fee
- Names real partner pharmacies (Strive, Striker) and lists phone support
Where it loses points
- Only 12 states served
- Membership required on top of the medical program
- Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.