Head-to-head · WeighScore
Loop Health vs SynergenX Health
The verdict
Loop Health takes it — 64.2/100 to 58.4/100.
Loop Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Loop Health | SynergenX Health |
|---|---|---|
| WeighScore | 64.2/100 | 58.4/100 |
| Grade | C | C |
| Scorecard rank | #244 | #374 |
| Semaglutide | $199/mo (all doses, microdosed, membership required, compounded) | $150/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide | $299/mo (all doses, microdosed, membership required, compounded) | Not disclosed |
| Coverage | All 50 states | 10 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #244 · C
Strengths
- Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
- Low membership entry point ($79/mo)
- Annual plan includes monthly 'research credit' toward compounds
- Explicit compounded-drug FDA disclaimer on-site
Where it loses points
- The medication price is on top of a $1,500-a-year membership, annual-plan only, which the terms confirm is separate from compound and medication costs
- Everything sold here is microdosed — the banner over both products reads 'MICRODOSED GLP-1', which is not a labelled therapeutic dose
- The prices exist only after the page's JavaScript runs; the served HTML body is empty
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Graded #374 · C
Strengths
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Where it loses points
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.