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Head-to-head · WeighScore

Loop Health vs SkyRx

Loop Health
Graded #244

Higher grade

vs+5.300000000000004
SkyRx
Graded #355

Lower grade

The verdict

Loop Health takes it — 64.2/100 to 58.9/100.

Loop Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSkyRx +12
44
56
Dose & formulationLoop Health +1
72
71
Clinical oversightLoop Health +11
79
68
Labs & monitoringLoop Health +21
73
52
FulfillmentLoop Health +14
78
64
Contract termsLoop Health +13
33
20
Loop Health · left barSkyRx · right bar

The numbers

MetricLoop HealthSkyRx
WeighScore64.2/10058.9/100
GradeCC
Scorecard rank#244#355
Semaglutide$199/mo (all doses, microdosed, membership required, compounded)$199/mo (all doses, 12-month plan, compounded)
Tirzepatide$299/mo (all doses, microdosed, membership required, compounded)Not disclosed
CoverageAll 50 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Loop Health

Graded #244 · C

Strengths

  • Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
  • Low membership entry point ($79/mo)
  • Annual plan includes monthly 'research credit' toward compounds
  • Explicit compounded-drug FDA disclaimer on-site

Where it loses points

  • The medication price is on top of a $1,500-a-year membership, annual-plan only, which the terms confirm is separate from compound and medication costs
  • Everything sold here is microdosed — the banner over both products reads 'MICRODOSED GLP-1', which is not a labelled therapeutic dose
  • The prices exist only after the page's JavaScript runs; the served HTML body is empty
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products
SkyRx

Graded #355 · C

Strengths

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Where it loses points

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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