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Head-to-head · WeighScore

Loop Health vs PCOS Sisters

Loop Health
Graded #244

Lower grade

vs+1.7999999999999972
PCOS Sisters
Graded #211

Higher grade

The verdict

PCOS Sisters takes it — 66/100 to 64.2/100, but only just.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required. Loop Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +18
44
62
Dose & formulationPCOS Sisters +16
72
88
Clinical oversightLoop Health +9
79
70
Labs & monitoringLoop Health +21
73
52
FulfillmentLoop Health +13
78
65
Contract termsPCOS Sisters +8
33
41
Loop Health · left barPCOS Sisters · right bar

The numbers

MetricLoop HealthPCOS Sisters
WeighScore64.2/10066/100
GradeCC
Scorecard rank#244#211
Semaglutide$199/mo (all doses, microdosed, membership required, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$299/mo (all doses, microdosed, membership required, compounded)$150/mo (plus a separate fee, compounded)
CoverageAll 50 states12 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
Loop Health

Graded #244 · C

Strengths

  • Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
  • Low membership entry point ($79/mo)
  • Annual plan includes monthly 'research credit' toward compounds
  • Explicit compounded-drug FDA disclaimer on-site

Where it loses points

  • The medication price is on top of a $1,500-a-year membership, annual-plan only, which the terms confirm is separate from compound and medication costs
  • Everything sold here is microdosed — the banner over both products reads 'MICRODOSED GLP-1', which is not a labelled therapeutic dose
  • The prices exist only after the page's JavaScript runs; the served HTML body is empty
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products
PCOS Sisters

Graded #211 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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