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Head-to-head · WeighScore

Loop Health vs Nucore Health

Loop Health
Graded #244

Higher grade

vs+5.600000000000001
Nucore Health
Graded #367

Lower grade

The verdict

Loop Health takes it — 64.2/100 to 58.6/100.

Loop Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLoop Health +8
44
36
Dose & formulationLoop Health +8
72
64
Clinical oversightNucore Health +3
79
82
Labs & monitoringLoop Health +20
73
53
FulfillmentLoop Health +11
78
67
Contract termsNucore Health +22
33
55
Loop Health · left barNucore Health · right bar

The numbers

MetricLoop HealthNucore Health
WeighScore64.2/10058.6/100
GradeCC
Scorecard rank#244#367
Semaglutide$199/mo (all doses, microdosed, membership required, compounded)$299/mo (starting dose, compounded)
Tirzepatide$299/mo (all doses, microdosed, membership required, compounded)$199/mo (microdose tier, compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Loop Health

Graded #244 · C

Strengths

  • Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
  • Low membership entry point ($79/mo)
  • Annual plan includes monthly 'research credit' toward compounds
  • Explicit compounded-drug FDA disclaimer on-site

Where it loses points

  • The medication price is on top of a $1,500-a-year membership, annual-plan only, which the terms confirm is separate from compound and medication costs
  • Everything sold here is microdosed — the banner over both products reads 'MICRODOSED GLP-1', which is not a labelled therapeutic dose
  • The prices exist only after the page's JavaScript runs; the served HTML body is empty
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products
Nucore Health

Graded #367 · C

Strengths

  • Physician-owned and LegitScript Certified — strong trust signals
  • Available nationwide in all 50 states
  • Care and pharmacy fulfillment run on OpenLoop Health's licensed network
  • Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12

Where it loses points

  • Published pricing is gated behind the intake quiz — no upfront cost shown
  • Legal terms and privacy are posted as downloadable documents, not web pages
  • Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
  • Longevity and microdose positioning is marketing; evidence varies by use

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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